systematic and comparative study on gene micro array using fuzzy logic applications

G.Gunasekaran,R.Rajeswari

Published in International Journal of Advanced Research in Computer Science Engineering and Information Technology

ISSN: 2321-3337          Impact Factor:1.521         Volume:3         Issue:1         Year: 26 June,2014         Pages:283-297

International Journal of Advanced Research in Computer Science Engineering and Information Technology

Abstract

Gene expression data is one of the most important areas that have emerged in the field of bioscience and medicine. There is a vast amount of data related with the gene expressions. The approach used for mining of the gene expression data is K-means clustering method while performing the retrievals and the computations parallel, thereby decreasing both the processing time and performing mining efficiently. The paper aims at solving the problem from the field of bioscience in the Engineering perspective.

Kewords

DATA MINING, Subspace clustering

Reference

1. Cho RJ, Campbell MJ, Winzeler EA, Steinmetz L, Conway A, Wodicka L, Wolfsberg TG, Gabrielian AE, Landsman D, Lockhart DJ, and Davis RW. A genome-wide transcriptional analysis of the mitotic cell cycle. Mol Cell 2: 65–73, 1998. 2. Cox E. Fuzzy fundamentals. IEEE Spectrum 29: 58–61, 1992. 3. Deckert J, Perini R, Balasubramanian B, and Zitomer RS. Multiple elements and auto-repression regulate Rox1, a repressor of hypoxic genes in Saccharomyces cerevisiae. Genetics Soc Am 139: 1149–1158, 1995. 4. Fytlovich S, Gervais M, Agrimonti C, and Guiard B. Evidence for an interaction between the CYP1(HAP1) activator and a cellular factor during heme-dependent transcriptional regulation in the yeast Saccharomyces cerevisiae. EMBO J 12: 1209–1218, 1993. 5. Hach A, Hon T, and Zhang L. A new class of repression modules is critical for heme regulation of the yeast transcriptional activator Hap1. Mol Cell Biol 19: 4324–4333, 1999. Abstract/FREE Full Text 6. Lodi T and Guiard B. Complex transcriptional regulation of the Saccharomyces cerevisiae CYB2 gene encoding cytochrome b2: CYP1 (HAP1) activator binds to the CYB2 upstream activation site UAS1-B2. Mol Cell Biol 11: 3762–3772, 1991. 7. Prezant T, Pfeifer K, and Guarente L. Organization of the regulatory region of the yeast cyc7 gene: multiple factors are involved in regulation. Mol Cell Biol 7: 3252–3259, 1987. 8. Schneider JC and Guarente L. Regulation of the yeast CYT1 gene encoding cytochrome c1 by HAP1 and HAP2/3/4. Mol Cell Biol 11: 4934–4942, 1991. 9. Tavazoie S, Hughes JD, Campbell MJ, Cho RJ, and Church GM. Systematic determination of genetic network architecture. Nat Genet 22: 281–285, 1999. 10. Zadeh LA. Fuzzy logic and its application to approximate reasoning. Information Processing 74: 591–594, 1974. 11. Zhang L, Hach A, and Wang C. Molecular mechanism governing heme signaling in yeast: a higher-order complex mediates heme regulation of the transcriptional activator HAP1. Mol Cell Biol 18: 3819–3828, 1998. 12. Zitomer RS, Limbach MP, Rodriguez-Torres AM, Balasubramanian B, Deckert J, and Snow PM. Approaches to the study of Rox1 repression of the hypoxic genes in the yeast Saccharomyces cerevisiae. Methods Enzymol 11: 279–288, 1997. 13. Lingras, P. “Rough Set Clustering for Web Mining”, Proceedings of 2002 IEEE International Conference on Fuzzy Systems. 2002. 14. Milligan G.W and Cooper M.C., “An examination of procedures for determining the number of clusters in a data set”, Psychometrika, vol. 50, pp. 159-179, 1985. 15. Monmarche N. Slimane M, and Venturini G. Antclass, “Discovery of cluster in numeric data by an hybridization of an ant colony with the k-means algorithm”, Technical Report 213, Ecole d’ Ingenieurs en Informatique pour l’Industrie (E3i), Universite de Tours, Jan. 1999. 16. Selim S. Z and Ismail M. A, “K-Means type algorithms: a generalized convergence theorem and characterization of local optimality,” in IEEE Transaction on Pattern Analysis and Machine Intelligence, vol. 6, No. 1, pp. 81--87, 1984. 17. Thangavel K and Ashok Kumar D, Department of Computer Science, “Simple Multi Pass Pattern Clustering Neural Networks”, AIML Journal, Vol. 5, Issue (3), Dec., 2005. 18. Tou J.T. and Gonzalez R.C., “Pattern Recognition Principles”, Massachusetts: Addision-Wesley, 1974. 19. Weiss SM and Indurkhya N. “Predictive Data Mining: a practical guide”, Morgan Kaufmann, 1998.