sharing and mining of rare drug reactions and symptoms

I.Roseleen Vino,D.Kerana Hanirex,K.P.Kaliyamurthie

Published in International Journal of Advanced Research in Computer Science Engineering and Information Technology

ISSN: 2321-3337          Impact Factor:1.521         Volume:3         Issue:1         Year: 26 June,2014         Pages:263-268

International Journal of Advanced Research in Computer Science Engineering and Information Technology

Abstract

Adverse Drug Reaction (ADR) is one of the greatest consequence in the evaluation of drug safety. Also, most of the adverse drug reactions are not discovered during limited pre-marketing clinical trials; but, they are only observed only after a long term post-marketing observation of drug usage.The exposure of adverse drug reaction,is an important method of research technique for the pharmaceutical industry. Recently, more number of adverse events and the improvement of data mining technology have motivated the development of statistical and data mining methods for the detection of Adverse drug reactions. These methods, without integration into the knowledge discovery systems, are very tedious and uncomfortable for users and the processe for exploration are time-consuming.

Kewords

Adverse drug reactions,data mining methods.

Reference

[1]Christopher C. Yang, Ling Jiang, Haodong Yang, Xuning Tang.” Detecting Signals of Adverse Drug Reactions from HealthConsumer Contributed Content in Social Media”.2012 [2] G. Niklas Norén · Johan Hopstadius · Andrew Bate · Kristina Star · I. Ralph Edwards.” Temporal pattern discovery in longitudinal electronic patient records”.2009 [3] A. Mansour, Y. Ji, H. Ying, R.M. Massanari, P. Dews, J. Tran, R.E. Miller, and “A Potential Causal Association Mining Algorithm for Screening Adverse Drug Reactions in Postmarketing Surveillance,” IEEE Trans. Information Technology in Biomedicine, 2011. [4] L. Szathmary, P. Valtchev and, A. Napoli, “Towards Rare Itemset Mining,” Proc IEEE 19th Int’l Conf. Tools with Artificial Intelligence,2007. [5] P.M. Doraiswamy, and A. Szarfman, , “Pharmacovigilance in the 21st Century: New Systematic Tools for an Old Problem,” Pharmacotherapy, , 2004. [6], H. He, G. Williams, H. Jin, J. Chen and C. Kelman, ,“Mining Unexpected Temporal Associations: Applications in the Detecting Adverse Drug Reactions,” IEEE Trans. Information Technology in Biomedicine, vol. 12, no. 4, pp. 488-500, July 2008. [7]Ji,H.Ying,M.S.Farber,J.Yen,”A Distributed,Collabrative Intelligent Agent Approach for Proactive Pastmarketing Drug Safety Surveillance,”IEEE Trans.InformationTechnology inBiomedicine,vol.14.no.3 Dec 2010. [8]B. Scho¨ lkopf and I. Guyon, D. Janzing,, “Causality: Objectives and Assessment,” JMLR Machine Learning Research Workshop and Conf. Proc., vol. 6, pp. 1-42, 2010.. [9] J. Pearl, Causality: Models, Reasoning and Inference, second ed. Cambridge Univ. Press, 2009. [10] Scho¨ lkopf, and I. Guyon, D. Janzing “Causality: Objectives and Assessment,” JMLR Machine Learning Research Workshop and Conf. Proc., vol. 6, pp. 1-42,2010. [11]I.Roseleen Vino,”Sharing and Mining of Rare Drug Reactions and Symptoms ” 2